KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
26.06
Human Site:
Y336
Identified Species:
44.1
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
Y336
E
N
S
G
L
A
L
Y
D
G
K
D
G
T
D
Chimpanzee
Pan troglodytes
XP_509445
540
59236
T175
L
Y
D
G
K
D
G
T
D
G
E
T
E
V
G
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
Y336
E
N
S
G
L
A
L
Y
D
G
K
D
S
T
D
Dog
Lupus familis
XP_534658
709
78944
Y336
E
N
S
G
L
A
L
Y
D
G
K
D
G
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
Y339
E
N
S
G
L
A
L
Y
D
G
N
D
D
A
D
Rat
Rattus norvegicus
NP_001099399
476
51796
L111
G
W
L
K
E
A
E
L
E
T
S
G
L
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
Y333
E
N
S
G
L
A
L
Y
D
G
K
D
A
T
D
Chicken
Gallus gallus
Q5F3D1
613
68449
Y248
N
E
T
E
D
E
G
Y
L
Q
P
K
H
V
T
Frog
Xenopus laevis
Q6DD45
743
82926
Y321
E
N
S
G
L
S
L
Y
D
G
K
E
R
L
D
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
Y320
E
N
S
G
L
M
L
Y
D
G
S
N
D
G
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
C188
A
Q
S
S
C
F
N
C
G
D
T
E
H
S
L
Honey Bee
Apis mellifera
XP_001122586
556
62911
K191
A
N
I
E
I
N
R
K
N
F
N
M
K
N
T
Nematode Worm
Caenorhab. elegans
P34656
453
51815
T88
W
R
K
R
L
E
C
T
L
L
G
S
V
S
T
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
L261
Y
I
Y
G
M
R
R
L
G
Y
P
P
G
H
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
20
93.3
93.3
N.A.
80
6.6
N.A.
93.3
6.6
73.3
66.6
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
26.6
93.3
93.3
N.A.
80
13.3
N.A.
93.3
13.3
86.6
73.3
N.A.
20
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
43
0
0
0
0
0
0
8
22
0
% A
% Cys:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
8
0
0
58
8
0
36
15
0
50
% D
% Glu:
50
8
0
15
8
15
8
0
8
0
8
15
8
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
65
0
0
15
0
15
58
8
8
22
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
15
8
0
% H
% Ile:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
8
0
0
8
0
0
36
8
8
0
0
% K
% Leu:
8
0
8
0
58
0
50
15
15
8
0
0
8
8
15
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
58
0
0
0
8
8
0
8
0
15
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
15
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
8
15
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
58
8
0
8
0
0
0
0
15
8
8
15
0
% S
% Thr:
0
0
8
0
0
0
0
15
0
8
8
8
0
22
22
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
15
0
% V
% Trp:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
8
0
0
0
0
58
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _